Helicobacter pylori persistence: biology and disease.

Blaser, Martin J; Atherton, John C · J Clin Invest · 2004

review · Level V

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Abstract

Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from person to person and to persistently colonize the stomach. Their population structure is a model for the ecology of the indigenous microbiota. A well-choreographed equilibrium between bacterial effectors and host responses permits microbial persistence and health of the host but confers risk of serious diseases, including peptic ulceration and gastric neoplasia.

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