Sleep. 2: pathophysiology of obstructive sleep apnoea/hypopnoea syndrome.

Fogel, R B; Malhotra, A; White, D P · Thorax · 2004

review · Level V

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Abstract

The pathogenesis of airway obstruction in patients with obstructive sleep apnoea/hypopnoea syndrome is reviewed. The primary defect is probably an anatomically small or collapsible pharyngeal airway, in combination with a sleep induced fall in upper airway muscle activity.

Medical subject headings