Plotting haplotype-specific linkage disequilibrium patterns by extended haplotype homozygosity.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 14764566.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Association studies may request more details of a specific haplotype. Haplotype-specific decay of linkage disequilibrium is such a crucial and versatile characteristic. It may be used, e.g. to search for signals of natural selection in a risk haplotype. Here, we present a web-based tool to explore the relationship between population frequency and extended linkage disequilibrium measured as haplotype homozygosity of observed haplotypes within a specified candidate region. The web-tool is available at http://ihg.gsf.de/cgi-bin/mueller/webehh.pl
Medical subject headings
- Chromosome Mapping
- Computer Graphics
- Gene Expression Profiling
- Haplotypes
- Linkage Disequilibrium
- User-Computer Interface