Coronary artery spasm and acute myocardial infarction in naproxen-associated anaphylactic reaction.

Cisteró, A; Urías, S; Guindo, J; Lleonart, R; Garcia-Moll, M; Geli, A; Bayés de Luna, A · Allergy · 1992

case_report · Level V

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Abstract

We present the case of a 43-year-old man who suffered an acute myocardial infarction after oral administration of 250 mg of naproxen, prescribed as antiinflammatory-analgesic agent after tooth extraction. Both intradermal skin test and human basophil degranulation test were positive to naproxen. These findings suggest a naproxen-associated anaphylactic reaction with concomitant coronary artery spasm and posteroinferior infarction, a clinical event previously not reported with the use of this drug.

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