Thrombolysis with low dose tissue plasminogen activator.
case_report · Level V
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- Record sourced from PubMed, PMID 1489229.
- Also identified by PMC identifier 1793968.
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Abstract
Two cases of vena caval thrombosis in infants were successfully treated with low dose (0.01-0.05 mg/kg/hour) local infusions of tissue plasminogen activator after conventional anticoagulant treatment had been unsuccessful. This approach is useful for clots associated with indwelling intravascular catheters, and a low dose infusion of tissue plasminogen activator as a regional application is recommended to achieve clot lysis with minimal systemic effects.
Medical subject headings
- Thrombolytic Therapy
- Thrombosis
- Tissue Plasminogen Activator