Acute uric acid nephropathy in pregnancy.

Alexopoulos, E; Tampakoudis, P; Bili, H; Mantalenakis, S · Obstet Gynecol · 1992

case_report · Level V

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Abstract

Although uric acid clearance increases during gestation, uric acid nephropathy is a rare cause of acute renal failure in the pregnant woman. A 38-year-old woman experienced acute renal failure due to acute uric acid nephropathy at 30 weeks' gestation. The diagnosis was based on extreme hyperuricemia and an elevated uric acid-creatinine ratio. Treatment with forced diuresis, urine alkalinization, and mannitol infusion resulted in a prompt and complete recovery of renal function. The woman ultimately gave birth to a healthy child. Acute uric acid nephropathy during pregnancy responds to conventional medical therapy.

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