Gene specific siRNA selector.
basic_science · Level V
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- Record sourced from PubMed, PMID 14960474.
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Abstract
Small interfering RNA (siRNA) is used in functional genomics applications to decrease the expression of a target gene, which may yield a biological effect that suggests a function for the target gene. The siRNA design tool scans a target gene for candidate siRNA sequences that satisfy user-adjustable rules. Selected candidates are then screened to identify those siRNA sequences that are specific to the gene of interest.
Medical subject headings
- Algorithms
- Computer-Aided Design
- RNA, Small Interfering
- Sequence Alignment
- Sequence Analysis, RNA
- Software