OBIYagns: a grid-based biochemical simulator with a parameter estimator.
basic_science · Level V
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Abstract
OBIYagns (yet another gene network simulator) is a biochemical system simulator that comprises a multiple-user Web-based graphical interface, an ordinary differential equation solver and a parameter estimators distributed over an open bioinformatics grid (OBIGrid). This grid-based biochemical simulation system can achieve high performance and provide a secure simulation environment for estimating kinetic parameters in an acceptable time period. OBIYagns can be applied to larger system biology-oriented simulation projects. OBIYagns example models, methods and user guide are available at https://access.obigrid.org/yagns/ Please refer to Bioinformatics online.
Medical subject headings
- Algorithms
- Cell Physiological Phenomena
- Computer Simulation
- Models, Biological
- Signal Transduction
- User-Computer Interface