Catastrophic kinesins: piecing together their mechanism by 3D reconstruction.
basic_science · Level V
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Abstract
Kin Is, kinesins with an internal catalytic domain, de-polymerize microtubules from both ends, and the KIF2C crystal structure presented by ([this issue of Cell]) provides provocative evidence to support the theory that the highly conserved sequences are critical structural elements in these catastrophic kinesins.
Medical subject headings
- Kinesins