Confirmation of the protective effect of iNOS in an independent cohort of Parkinson disease.

Hague, S; Peuralinna, T; Eerola, J; Hellström, O; Tienari, P J; Singleton, A B · Neurology · 2004

case_control · Level III

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Abstract

Nitric oxide is a biologic messenger molecule involved in a diverse range of physiologic processes. An exon 22 inducible nitric oxide synthase genotype has recently been reported to be protective against Parkinson disease in a European cohort. The authors confirm the protective effect of this genotype (OR = 0.5, 95% CI 0.27 to 0.93) in an independent Finnish case-control series.

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