Interstitial radiosurgery in the treatment of gelastic epilepsy due to hypothalamic hamartomas.

Schulze-Bonhage, A; Homberg, V; Trippel, M; Keimer, R; Elger, C E; Warnke, P C; Ostertag, C · Neurology · 2004

case_series · Level IV

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Abstract

The authors evaluated a new stereotactic radiosurgical approach in seven patients with gelastic epilepsy due to hypothalamic hamartomas. Stereotactic implantation of 125I-seeds into the hamartoma was feasible in six patients. At follow-up at least 1 year after interstitial radiotherapy, two patients had become seizure-free within 2 months, and two others had only persisting auras. There were no major perioperative or postoperative side effects.

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