Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging.

Wang, Fei; Sun, Zhiguo; Cui, Liwei; Du, Xiangke; Wang, Xilin; Zhang, Hongyan; Cong, Zhong; Hong, Nan et al. · Am J Psychiatry · 2004

case_control · Level III

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Abstract

This study used diffusion tensor imaging to examine fractional anisotropy in the anterior cingulum and posterior cingulum bundles in patients with schizophrenia. Twenty-one male patients and 20 healthy comparison men were studied. Reduced fractional anisotropy was seen for both sides of the anterior cingulum in the schizophrenia patients, who also exhibited less left-greater-than-right asymmetry in the anterior cingulum than was seen in the comparison subjects. The findings suggest structural disconnections in the anterior cingulum in patients with schizophrenia.

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