Science imitates art: the cloning of mice from olfactory sensory neurons.
review · Level V
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- Record sourced from PubMed, PMID 15006346.
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Abstract
The functional identity of an olfactory sensory neuron is defined by its expression of one odorant receptor from a large multigene family. The complexity of this process has led to speculation that DNA rearrangements are used to limit the expression of one receptor gene per cell. However, a recent report in Nature directly rules out irreversible DNA rearrangements as a mechanism for odorant receptor gene choice.
Medical subject headings
- Cloning, Organism
- Olfactory Receptor Neurons
- Receptors, Odorant