Bull's-eye maculopathy associated with quinacrine therapy for malaria.
case_report · Level V
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Abstract
To report a side effect of quinacrine therapy for malaria. Case report. Review of clinical chart and photographs. Private retina practice. A patient developed a bilaterally symmetric bull's-eye maculopathy 45 years after taking quinacrine for 18 months as prophylaxis against malaria. Progression of the clinical picture was documented over 15 years of follow-up. The clinical picture was identical to that of chloroquine and hydroxychloroquine maculopathy. Low dosages of quinacrine used for malaria prophylaxis can be associated with a delayed, severe maculopathy indistinguishable from chloroquine maculopathy in certain patients.
Medical subject headings
- Antimalarials
- Malaria, Vivax
- Quinacrine
- Retinal Diseases