Socializing with the neighbors: stem cells and their niche.
review · Level V
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Abstract
The potential of stem cells in regenerative medicine relies upon removing them from their natural habitat, propagating them in culture, and placing them into a foreign tissue environment. To do so, it is essential to understand how stem cells interact with their microenvironment, the so-called stem cell niche, to establish and maintain their properties. In this review, we examine adult stem cell niches and their impact on stem cell biology.
Medical subject headings
- Cell Communication
- Cell Differentiation
- Cell Lineage
- Embryo, Mammalian
- Organogenesis
- Stem Cells