Reversible diffusion MRI abnormalities and transient mutism after liver transplantation.

Bianco, F; Fattapposta, F; Locuratolo, N; Pierallini, A; Rossi, M; Ruberto, F; Bozzao, L · Neurology · 2004

case_report · Level V

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Abstract

Transient mutism was observed in a liver transplant patient under immunosuppressant therapy with cyclosporine A and antifungal prophylaxis with amphotericin B. Fluid-attenuated inversion recovery and diffusion-weighted images revealed reversible bilateral symmetric hyperintensity located in the frontal motor cortex and corticospinal tracts. These MRI abnormalities may be caused by acute edema, possibly a combination of cytotoxic and vasogenic edema, which resolved with a prompt change in therapy.

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