A genetic algorithm for the detection of new cis-regulatory modules in sets of coregulated genes.
basic_science · Level V
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Abstract
The implementation of a genetic algorithm is described that provides a fast method of searching for the optimal combination of transcription factor binding sites in a set of regulatory sequences. The algorithm can be used transparently as a web service from within the Toucan software. Toucan can be accessed at http://www.esat.kuleuven.ac.be/~saerts/software/toucan.php. A standalone version of the software is available upon request.
Medical subject headings
- Algorithms
- Chromosome Mapping
- Gene Expression Profiling
- Gene Expression Regulation
- Genes, Regulator
- Sequence Alignment
- Sequence Analysis, DNA