Dengue: defining protective versus pathologic immunity.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 15057297.
- Also identified by PMC identifier 379334.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Dengue is an expanding public health problem, and an effective vaccine remains elusive. This review discusses how the significant influence of sequential infection with different dengue virus serotypes on the severity of disease can be viewed in terms of beneficial and detrimental effects of heterologous immunity. A more complete understanding of these effects is likely to be critical for predicting optimal vaccine-induced immune responses.
Medical subject headings
- Dengue
- Immune System