Ig V region restrictions in human chronic lymphocytic leukemia suggest some cases have a common origin.
editorial · Level V
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- Record sourced from PubMed, PMID 15057298.
- Also identified by PMC identifier 379330.
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Abstract
The factors that contribute to the development of B cell chronic lymphocytic leukemia (B-CLL) are unknown, and the groups of individuals at the greatest risk for developing this common leukemia are not well defined. Molecular features are important for classifying cases of B-CLL, and it is now apparent that similarities among Ig rearrangements between patients may give important clues to the origin of this disease.
Medical subject headings
- Immunoglobulin Variable Region
- Leukemia, Lymphocytic, Chronic, B-Cell