SCANMS: adjusting for multiple comparisons in sliding window neutrality tests.
other · Level V
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- Record sourced from PubMed, PMID 15059827.
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Abstract
A Perl utility called SCANMS was written that operates on parametric bootstrap data generated by Hudson's simulator MS. SCANMS simulates sliding window analysis of Tajima's D or Fu and Li's D(*) or F(*) over the replicates and generates the empirical joint distribution of window minima and maxima. This distribution may then be used to calculate achieved significance values or significance cutoffs that account for multiple comparisons in sliding window analysis of real data. SCANMS is available free of charge under the terms of the Academic Free License 2.0 and may be downloaded from http://www.lcb.uu.se/~dave/SCANMS
Medical subject headings
- Algorithms
- Numerical Analysis, Computer-Assisted
- Sequence Alignment
- Sequence Analysis, DNA
- Software