The immune response to AIDS virus infection: good, bad, or both?
editorial · Level V
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- Record sourced from PubMed, PMID 15067312.
- Also identified by PMC identifier 362127.
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Abstract
A potent antigen-specific T cell response to HIV infection can contribute to the control of viral replication and is therefore beneficial to the host. However, HIV-mediated increases in generalized T cell activation also appear to accelerate both viral replication and CD4+ T cell depletion. A new study in the JCI attempts to experimentally distinguish the beneficial versus harmful aspects of this immune response.
Medical subject headings
- HIV Infections
- HIV-1