Cerebral edema associated with betaine treatment in classical homocystinuria.

Devlin, A M; Hajipour, L; Gholkar, A; Fernandes, H; Ramesh, V; Morris, A A M · J Pediatr · 2004

case_report · Level V

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Abstract

A child with cystathionine beta-synthase deficiency developed cerebral edema 4 to 6 weeks after starting betaine therapy. There was no evidence of intracranial thrombosis, but there was widespread edema of the white matter. He recovered fully after emergency decompressive craniotomy and withdrawal of betaine.

Medical subject headings