111Indium-oxine-labeled leukocytes and 67gallium-citrate as indicators of renal injury following extracorporeal shock wave lithotripsy.

Abstract

To document the extent and persistence of traumatic inflammation after extracorporeal shock wave lithotripsy (ESWL), 15 patients were randomly chosen to have either 67gallium (67Ga)-citrate or 111indium (111In)-oxine scans within 24 to 48 hours of ESWL. Positive scans were repeated at 8 to 12 weeks. Nine patients had renal calculi, and 6 had ureteral calculi and acted as controls. Of the patients with renal calculi 6 were scanned with 67Ga-citrate and 3 with 111In-oxine. Four of the former and 2 of the latter scans showed evidence of renal injury. Followup scans were normal. There was no correlation between power index (number of shocks times accelerating voltage) and scan results. Half of the control subjects were scanned with 67Ga-citrate and the remainder with 111In-oxine and all scans were negative. 67Ga-citrate and 111In-oxine scans can show evidence of renal injury immediately after ESWL but abnormal scans 2 to 3 months later would be suggestive of a different inflammatory process.