Behavioral symptoms in mild cognitive impairment.

Feldman, H; Scheltens, P; Scarpini, E; Hermann, N; Mesenbrink, P; Mancione, L; Tekin, S; Lane, R et al. · Neurology · 2004

cross_sectional · Level IV

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Abstract

The authors investigated neuropsychiatric symptoms in mild cognitive impairment (MCI) from baseline data of the Investigation in the Delay to Diagnosis of AD with Exelon (InDDEx) study (n = 1,010). Neuropsychiatric symptoms were reported in 59% of subjects (Neuropsychiatric Inventory [NPI]). NPI+ subjects had significantly greater impairment on global, cognitive, and functional scores than NPI- subjects. The presence of neuropsychiatric symptoms appears to be a marker of MCI severity.

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