Leukoencephalopathy, cerebral calcifications, and cysts: new observations.

Nagae-Poetscher, L M; Bibat, G; Philippart, M; Rosemberg, S; Fatemi, A; Lacerda, M T C; Costa, M O R; Kok, F et al. · Neurology · 2004

case_series · Level IV

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Abstract

We describe three cases of the rare syndrome of leukoencephalopathy, brain calcifications, and cysts. Conventional MRI, proton spectroscopy, and diffusion-weighted imaging yielded additional information on the disease. Imaging findings favor increased water content rather than a demyelinating process in the pathophysiology of this disease. Clinical features of Coats disease and consanguinity were also encountered.

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