Cognitive functioning in humans with mutations of the PAX6 gene.
case_series · Level IV
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- Record sourced from PubMed, PMID 15079031.
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Abstract
Fourteen patients with PAX6 gene mutations and previously identified MRI abnormalities were administered tests of cognitive functioning. No deficits were found. A subgroup with agenesis of the anterior commissure performed significantly more poorly on measures of working memory than those without this abnormality, suggesting the anterior commissure may play a role in cognitive processing in addition to an earlier identified role in sensory development and processing.
Medical subject headings
- Cognition
- Cognition Disorders
- Homeodomain Proteins
- Mutation