Hepcidin and its role in iron absorption.
review · Level V
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- Record sourced from PubMed, PMID 15082573.
- Also identified by PMC identifier 1774051.
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Abstract
Maintaining the correct iron balance is crucial to good health. Disorders of iron homeostasis have a global distribution. As iron is not actively excreted by the body, understanding the role of proteins involved in regulating iron uptake is essential to our understanding of disease involving iron homeostasis. Over the past 10 years, major advances have been made in understanding the genetics of iron metabolism and this has led to identification of a number of new proteins, including hepcidin, involved in iron homeostasis.
Medical subject headings
- Antimicrobial Cationic Peptides
- Iron