Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia.

Vavricka, S R; Halter, J; Hechelhammer, L; Himmelmann, A · Postgrad Med J · 2004

case_report · Level V

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Abstract

Pneumocystis carinii pneumonia in patients with chronic lymphocytic leukaemia (CLL) who have not been treated with fludarabin are rare, although clinically relevant CD4 T-cell depletion can occur in longstanding CLL without prior treatment with purine analogues. A 52 year old woman is reported who was on long term treatment with chlorambucil and taking a short course of prednisone for familial CLL before she developed progressive dyspnoea, and P carinii pneumonia was diagnosed in bronchoalveolar lavage fluid. Despite treatment with high dose co-trimoxazole the patient died.

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