Reversible bilateral internuclear ophthalmoplegia associated with FK506.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 15090580.
- Also identified by PMC identifier 1763581.
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Abstract
A 50 year old man developed tonic-clonic seizures while receiving cyclosporin A after orthotopic cardiac transplant. The seizures resolved after cessation of cyclosporin A. Thirteen months later, he developed diplopia from bilateral internuclear ophthalmoplegia while receiving intravenous FK506. A temporal association was found between his symptoms and the serum FK506 concentrations. Withdrawal of the intravenous FK506 led to prompt resolution of the bilateral internuclear ophthalmoplegia.
Medical subject headings
- Heart Transplantation
- Immunosuppressive Agents
- Ocular Motility Disorders
- Tacrolimus