Failure of low-dose atovaquone prophylaxis against Pneumocystis jiroveci infection in transplant recipients.
case_report · Level V
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Abstract
Trimethoprim-sulfamethoxazole is the preferred agent for prophylaxis against Pneumocystis jiroveci pneumonia. Alternative agents are used in treating patients who do not tolerate this medication. We report 2 cases of prophylaxis failure in patients receiving low-dose atovaquone. We discuss the use of atovaquone as an alternative agent for prophylaxis in transplant recipients.
Medical subject headings
- Antifungal Agents
- Naphthoquinones
- Opportunistic Infections
- Pneumocystis carinii
- Pneumonia, Pneumocystis