Early proximal tubular dysfunction in Lowe's syndrome.

Laube, G F; Russell-Eggitt, I M; van't Hoff, W G · Arch Dis Child · 2004

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Abstract

The early diagnosis of Lowe's syndrome can be difficult. Urinary excretion of retinol binding protein (RBP) and the lysosomal enzyme N-acetyl-glucosaminidase (NAG) were significantly increased in boys with Lowe's syndrome. Measurement of these urine parameters is recommended in suspected cases.

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