Gene-Ontology-based clustering of gene expression data.
basic_science · Level V
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- Record sourced from PubMed, PMID 15117760.
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Abstract
The expected correlation between genetic co-regulation and affiliation to a common biological process is not necessarily the case when numerical cluster algorithms are applied to gene expression data. GO-Cluster uses the tree structure of the Gene Ontology database as a framework for numerical clustering, and thus allowing a simple visualization of gene expression data at various levels of the ontology tree. The 32-bit Windows application is freely available at http://www.mpibpc.mpg.de/go-cluster/
Medical subject headings
- Database Management Systems
- Databases, Protein
- Gene Expression Profiling
- Proteins
- Software
- User-Computer Interface