A pediatric cluster of Shigella dysenteriae serotype 1 diarrhea with hemolytic uremic syndrome in 2 families from France.

Houdouin, Véronique; Doit, Catherine; Mariani, P; Brahimi, Naïma; Loirat, Chantal; Bourrillon, Antoine; Bingen, Edouard · Clin Infect Dis · 2004

case_series · Level IV

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Abstract

We report a cluster of pediatric diarrhea due to Shigella dysenteriae serotype 1 involving 11 children in France, including the index case, who had returned from Senegal. Child-to-child transmission was documented by ribotyping. Five children developed hemolytic uremic syndrome (HUS). On the basis of our findings, the choice of antimicrobial treatment for infections with S. dysenteriae serotype 1 should take into account widespread drug resistance and the risk of HUS.

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