Metabolism of glucurolactone to glucarate in Parkinson's disease.

Koller, W C; Rope, S D; Huber, S J; Blumenthal, D C; Blumenthal, H J · Neurology · 1992

case_control · Level III

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Abstract

The metabolism of oral glucurolactone to serum D-glucarate by the hepatic cytochrome P450 enzyme system was no different in 20 untreated Parkinson's disease (PD) patients as compared with 20 age- and sex-matched controls. There was no evidence for a deficit in hepatic enzymes in PD.

Medical subject headings