Gamete interruptus; a novel calcium-dependent kinase is essential for malaria sexual reproduction.
basic_science · Level V
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Abstract
Malaria parasites undergo sexual fertilization minutes after the bloodmeal enters the mosquito midgut. In this issue of Cell, Billker et al. (2004) describe a new Plasmodium calcium-dependent protein kinase essential for gamete formation, and show that it is required for parasite transmission.
Medical subject headings
- Germ Cells
- Plasmodium
- Protein Kinases
- Reproduction