Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 15146232.
- Also identified by PMC identifier 406535.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.
Medical subject headings
- Autoantibodies
- Heart Failure
- Receptors, Adrenergic, beta-1