Tutorial section: domains and motifs - proteins in bite-sized chunks.

Mullan, Lisa · Brief Bioinform · 2004

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Abstract

Possibly the ultimate goal of bioinformatics is to be able to predict protein tertiary structure and chemical functionality from the initial amino acid sequence. Despite the best efforts of many researchers over the past two decades, a reliable modelling method has yet to be found and the folding problem continues to be a hurdle for scientists.

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