Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study.
case_report · Level V
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- Record sourced from PubMed, PMID 15153889.
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Abstract
Nocturnal pruritus is a significant problem for patients with inflammatory skin diseases and many systemic diseases. The oral therapies currently available have a limited effect. We present an open, uncontrolled pilot study of 3 patients with inflammatory skin diseases and severe nocturnal pruritus who underwent treatment with mirtazapine (Remeron), a noradrenergic and specific serotonergic antidepressant. Mirtazapine is a safe medication without serious side effects and may be an effective alternative for the treatment of nocturnal pruritus.
Medical subject headings
- Adrenergic alpha-Antagonists
- Antidepressive Agents, Tricyclic
- Mianserin
- Pruritus