Treatment of extensive chronic cutaneous graft-versus-host disease in an infant with topical pimecrolimus.

Ziemer, Mirjana; Gruhn, Bernd; Thiele, Jens J; Elsner, Peter · J Am Acad Dermatol · 2004

case_report · Level V

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Abstract

We report a case of generalized cutaneous chronic graft-versus-host disease in a 17-month-old infant. Topical treatment with the novel ascomycin substance pimecrolimus once daily for 4 weeks led to a near complete clearance of skin lesions. Importantly, this excellent clinical response was obtained without additional use of systemic immunosuppressive treatment.

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