Class II MHC: sweetening the peptide only diet?
review · Level V
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- Record sourced from PubMed, PMID 15163404.
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Abstract
MHC molecules typically bind peptides to create ligands for the T cell antigen receptor. In this issue of Cell, report an unexpected association of class II MHC molecules with processed zwitterionic polysaccharides from pathogenic bacteria. The complexes appear to modulate the T cell dependent pathology of abscess formation.
Medical subject headings
- Histocompatibility Antigens Class II
- Peptides