Automatic annotation of organellar genomes with DOGMA.
basic_science · Level V
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- Record sourced from PubMed, PMID 15180927.
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Abstract
The Dual Organellar GenoMe Annotator (DOGMA) automates the annotation of organellar (plant chloroplast and animal mitochondrial) genomes. It is a Web-based package that allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. DOGMA provides a graphical user interface for viewing and editing annotations. Annotations are stored on our password-protected server to enable repeated sessions of working on the same genome. Finished annotations can be extracted for direct submission to GenBank.
Medical subject headings
- Chromosome Mapping
- Databases, Genetic
- Documentation
- Information Storage and Retrieval
- Organelles
- Software
- User-Computer Interface