Prediction of protein folding rates from the amino acid sequence-predicted secondary structure.
basic_science · Level V
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- Record sourced from PubMed, PMID 15184682.
- Also identified by PMC identifier 428451.
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Abstract
We present a method for predicting folding rates of proteins from their amino acid sequences only, or rather, from their chain lengths and their helicity predicted from their sequences. The method achieves 82% correlation with experiment over all 64 "two-state" and "multistate" proteins (including two artificial peptides) studied up to now.
Medical subject headings
- Protein Folding
- Proteins