Cleft palate: players, pathways, and pursuits.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 15199400.
- Also identified by PMC identifier 420516.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Cleft lip and palate is a common human birth defect, and its causes are being dissected through studies of human populations and through the use of animal models. Mouse models in particular have made a substantial contribution to our understanding of the gene pathways involved in palate development and the nature of signaling molecules that act in a tissue-specific manner at critical stages of embryogenesis. Related work has provided further support for investigating the role of common environmental triggers as causal covariates.
Medical subject headings
- Cleft Palate