Life-threatening allergic reaction to clozapine.
case_report · Level V
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- Record sourced from PubMed, PMID 1521111.
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Abstract
Clozapine, an 'atypical' antipsychotic drug, rarely induces allergic complications, which usually present as cutaneous reactions. We report the case of a 69-year-old woman, suffering from chronic schizophrenia, who developed an allergic asthmatic reaction following clozapine therapy. Intensive-care treatment was necessary. The reaction could be repeated by further exposure to the drug. Skin tests for hypersensitivity were negative.
Medical subject headings
- Asthma
- Clozapine
- Drug Hypersensitivity
- Schizophrenia, Paranoid