A noninflammatory pathway for pregnancy loss: innate immune activation?
review · Level V
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- Record sourced from PubMed, PMID 15232605.
- Also identified by PMC identifier 437974.
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Abstract
Although the mechanisms of immune-mediated pregnancy loss are unknown, investigations are currently focused on mediators of immune activation and tissue injury at the maternal-fetal interface. A new study, however, demonstrates that systemic inflammatory mediators can induce pregnancy failure in a different way, by inhibiting ovarian hormone production, and identifies links between the immune and reproductive endocrine systems.
Medical subject headings
- Abortion, Spontaneous