Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats.
basic_science · Level V
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- Record sourced from PubMed, PMID 15236876.
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Abstract
The purpose of this study was to investigate whether application of post-irradiation vitamin E, an anti-oxidant, could prevent the development of radiation induced lung damage. Wistar rats were given vitamin E enriched or vitamin E deprived food starting from 4 weeks after 18Gy single dose irradiation of the right thorax. Neither breathing frequencies nor CT density measurements revealed differences between the groups. It is concluded that post-irradiation vitamin E does not influence radiation-induced fibrosis to the lung.
Medical subject headings
- Antioxidants
- Radiation Pneumonitis
- Vitamin E