Anti-basal ganglia antibodies in patients with atypical dystonia and tics: a prospective study.
prospective_cohort · Level II
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Abstract
Anti-basal ganglia antibodies (ABGA) are associated with movement disorders in children, but have not been assessed in adult onset movement disorders. In a prospective assessment ABGA were positive in 65% of a group of 65 patients with atypical movement disorders, but were very rare in healthy adults and adults with idiopathic dystonia. An autoimmune mechanism may underlie a proportion of cases of atypical movement disorders.
Medical subject headings
- Autoantibodies
- Basal Ganglia
- Dystonia
- Tics