A complete and durable clinical response to high-dose dexamethasone in a patient with scleromyxedema.

Horn, Keren B; Horn, Meyer A; Swan, James; Singhal, Seema; Guitart, Joan · J Am Acad Dermatol · 2004

case_report · Level V

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Abstract

We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associated paraproteinemia.

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