Anaphylaxis in immunotherapy.

Davis, W E; Cook, P R; McKinsey, J P; Templer, J W · Otolaryngol Head Neck Surg · 1992

case_series · Level IV

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Abstract

Although anaphylactic reactions resulting from immunotherapy rarely occur, when they do occur they can be life-threatening. The literature reveals more than 30 deaths attributed to immunotherapy but numerous reports of anaphylaxis. We reviewed a 5-year experience of immunotherapy in a University practice and their experience with systemic reactions is presented. More than 125,000 injections were given in this time period. Of the 550 patients receiving immunotherapy, 14% experienced anaphylactic reactions, the majority of which were mild.

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