Pulmonary fibrosis: thinking outside of the lung.

Garantziotis, Stavros; Steele, Mark P; Schwartz, David A · J Clin Invest · 2004

review · Level V

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Abstract

Pulmonary fibrosis is a devastating condition that leads to progressive lung destruction and scarring. Previous mechanistic research has focused on the local fibroproliferative process in the lung. However, emerging evidence suggests that circulating cells of hematopoietic origin play a crucial role in the pathogenesis of this disease.

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